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Enterobacteriaceae are gram negative rods
2020-11-27

Enterobacteriaceae are gram negative rods that include the Escherichia coli and Shigella. There are several DNA ligases posted on the GenBank belong mostly to Enterobacteria phages, such as the T4 bacteriophage [30]. There are several protein markers used to differentiate between T4 phage superfamil
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Introduction Collagen deposition is a common feature found i
2020-11-26

Introduction Collagen deposition is a common feature found in cancerous tissues and fibrotic organs/lesions. It is now well accepted that collagen deposition is not just a consequence of disease, but that it can also trigger a vicious cycle. Both chemical and physical signals elicited from collagen
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Cysteinyl leukotrienes CysLTs are potent
2020-11-26

Cysteinyl leukotrienes (CysLTs) are potent inflammatory mediators closely associated with cerebral ischemic injury. CysLTs induce inflammatory responses mediated by at least two different CysLT receptors (CysLT1R and CysLT2R) (Bäck et al., 2011, Singh et al., 2010). It has been reported that the Cys
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In present study we measured the methylation
2020-11-26

In present study, we measured the methylation and TPMPA levels of CDKL2 in HCC tissues and cell lines. Meanwhile, correlations between the methylation and mRNA expression, clinicopathological features were evaluated. Materials and methods Results Discussion DNA methylation is a heritable
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Prostaglandins PGs are lipid mediators
2020-11-26

Prostaglandins (PGs) are lipid mediators that exhibit a variety of physiological properties by interacting specific G protein-coupled receptors (GPCRs) [10]. PGD2 is synthesized from PGH2 through two distinct PGD synthases; lipocalin-type PGD synthase (L-PGDS) and hematopoietic PGD synthase (H-PGDS)
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DDX belongs to the DEAD box family
2020-11-26

DDX3 belongs to the DEAD-box family of proteins, ATP-dependent RNA helicases characterized by the presence of a highly conserved helicase core domain [13]. This catalytic core is composed of two RecA-like domains containing motifs involved in ATP binding/hydrolysis, RNA binding and helicase activity
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CPG a metalloenzyme derived from sp was the
2020-11-26

CPG2, a metalloenzyme derived from sp., was the elected enzyme for the first pilot-scale clinical trial of ADEPT. This enzyme has no mammalian homologue and activates glutamic (+)-MK 801 prodrug derivatives of several nitrogen mustards alkylating agents., , , , , A bond cleavable by CPG2 is essen
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Application of the CPH model
2020-11-26

Application of the CPH model relies on the assumption that the hazard ratio of two observations is constant over time [2]. This enables us to infer the rate of risk of the treatment. For example, in the study of patients with pulmonary arterial hypertension (PAH) [5], the hazard ratio of a group of
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br Discussion Personality develops throughout a human s life
2020-11-26

Discussion Personality develops throughout a human's life and is related to his or her innate temperament. While personality features are shaped by various experiences of daily life and moderate a wide range of specific behaviours related to particular situational contexts, temperament reveals it
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Introduction Hematopoietic stem cells HSCs in the adult bone
2020-11-26

Introduction Hematopoietic stem simvastin (HSCs) in the adult bone marrow (BM) provide all types of blood cells throughout life, while also self-renewing to maintain blood homeostasis. Blood/marrow stem cell transplantation is the most advanced method to cure patients suffering from hematological
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br Experimental br Results and
2020-11-26

Experimental Results and discussion On the basis of the information obtained from the studies on RHA/TiO2 nanocomposites, it S/GSK1349572 is expected that this reagent can be used as a catalyst for the promotion of the organic reactions. So this reagent was used in the promotion of the conver
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br Materials and methods br Results and discussion br
2020-11-26

Materials and methods Results and discussion Conclusions The current research work deals with preparation of CES from RHA and comparative study of Ni (II) ion adsorption on CES and RHA. It was observed that carbon embedded silica shows more porous structure and more surface area as compared
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The Ewing sarcoma breakpoint region gene EWSR
2020-11-26

The Ewing sarcoma breakpoint region 1 gene (EWSR1) is a partner in a large, diverse range of mesenchymal (and some nonmesenchymal) tumors (Tables 1 and 2). As the 5′ partner, EWSR1 is able to fuse with an array of genes. These fusions can generate genetically different but phenotypically identical n
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We recently employed a functional drug screening approach to
2020-11-26

We recently employed a functional drug screening approach to identify mithramycin as an inhibitor of EWS–FLI1. In our study, we employed a stepwise approach involving a luciferase primary screen and a novel multiplex PCR screen to evaluate over 50,000 compounds to identify mithramycin as an inhibito
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In addition to PGC transcriptional co repressors such as NCO
2020-11-26

In addition to PGC1α, transcriptional co-repressors such as NCOR and RIP140 participate in oxidative muscle remodeling induced by exercise, whereby reductions in their expression and the resulting de-repression of downstream TFs activates oxidative gene expression (Seth et al., 2007, Yamamoto et al.
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