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When a psoriasis patient shows primary or secondary failure
2018-11-12
When a psoriasis patient shows primary or secondary failure or has adverse effects to one biologic agent, shifting to use another biologic agent of either the same or different mode of action should be considered. Psoriasis could impair patients’ quality of life significantly. New biologics not only
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A variant of MF with CD
2018-11-12
A variant of MF with CD20 expression was considered in the differential diagnosis of our patient. Those cases have revealed typical features of MF on histological examination. However, neoplastic T cells were strongly positive for CD20 but not for other B-cell markers, namely, CD79a, CD19, and PAX5.
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Xi di is one of the
2018-11-12
Xi-di is one of the most famous ancient villages (Figure 1) in China, with a long history tracing back to the Song dynasty (A.D. 960–1279). The development of the village occurred during the period of the Ming dynasty, followed by prosperity in early Qing dynasty and downfall afterwards. More recen
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Thompson transformations parametric warping based on quadrat
2018-11-12
Thompson transformations (parametric “warping” based on quadratic functions, Wilkinson, 2005, pp. 223–224) as illustrated in Figure 3 allow positive and negative transformations based on parameters P1–P10. Of these, the presented generative system uses the six parameters P1, P2, P3, P6, P7 and P8. P
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br Acknowledgments This work was supported by the
2018-11-12
Acknowledgments This work was supported by the Munich University of Applied Sciences and the Labor fuer Stahl- und Leichtmetallbau GmbH, Munich, Germany. Introduction Chen (2004) explores the use of computational tools to factor wind into architectural environmental design. The study compares
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We ignore the names of
2018-11-12
We ignore the names of the owners and the identity of the tenants of the two domus. However, according to the location at the centre of the Urbs (city) near the Imperial Fora and according to their dimensions (over 1000m2) and plan, typical of important late Roman domus, we may suppose that they wer
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br Results Of the patients using this
2018-11-12
Results Of the 28 patients using this technique, the mean age at diagnosis was 63.2 years (range: 45–81 years). There were 18 men and 10 women. The mean surgical time was 253 minutes (range: 170–275 minutes). The mean estimated blood loss was 120mL (range: 70–350mL). The mean hospital stay was 6.
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Soon after admission the muscle
2018-11-12
Soon after admission, the muscle power in the patient\'s four limbs deteriorated to Grade 1-2 of 5. A contrast-enhanced MRI of the cervical spine revealed an intramedullary oval lesion with a linear enhancement around the margin. This extended from C2 to C4 on T1WI (Fig. 2). An ISCA was the leading
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For symptomatic appendiceal diverticulitis an
2018-11-12
For symptomatic appendiceal diverticulitis, an appendectomy is the optimal treatment. Regarding whether patients without symptoms require an appendectomy, most surgeons suggest a prophylactic appendectomy because, even in symptomless patients, the risk of perforation and mortality is higher in these
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For end stage renal failure patients
2018-11-12
For end-stage renal failure patients, secondary hyperparathyroidism followed by hyperphosphatemia is not uncommon. According to the 2012 United States Renal Data System Annual Data Report, the prevalence of ESRD patients in Taiwan is highest in the world, at 2584 per million population. Additionally
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At least two subpopulations of activated macrophages coexist
2018-11-12
At least two subpopulations of activated macrophages coexist in a tumor microenvironment. The first subpopulation is the classically activated macrophages (i.e., M1 macrophages), characterized by the IL-12high, -23high, and -10low phenotypes; these macrophages can produce TNF-α and nitric oxide. The
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Introduction Malignant fibrous histiocytoma MFH is
2018-11-12
Introduction Malignant fibrous histiocytoma (MFH) is a pleomorphic sarcoma originally described by Ozzello et al in 1963 and O\'Brien and Stout in 1964. It is one of the most common soft-tissue sarcomas among adults, with a peak incidence between 60 and 70 years of age. It has been determined to ex
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Current evidence indicates that the main
2018-11-12
Current evidence indicates that the main reservoirs of zoonotic Cryptosporidium remain livestock, with the potential transmission of C. parvum (= C. pestis (see Slapeta, 2011)), although other species, and genotypes, have been reported in humans but only occasionally (Slapeta, 2013). Susceptibility
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br Materials and Methods br Results
2018-11-12
Materials and Methods Results Discussion Liver participates in a variety of enzymatic metabolic activities. Administration of ethanol causes elevation of serum ASP, ALT, ALP and total bilirubin levels in rats, indicating that ethanol may induce hepatocellular damages which in turn alters th
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Of the population that does respond to
2018-11-12
Of the population that does respond to the peptides with changes in chronotropy ET-1, acting via ETA receptors, elicited a PKC-dependent, pertussis toxin- and 2-APB-insensitive positive chronotropic response. This finding is broadly consistent with a previous study in mESC-CMs (Kapur and Banach, 200
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