• br Introduction Nonalcoholic fatty liver disease NAFLD

  2023-10-09

  

  Introduction Nonalcoholic fatty liver disease (NAFLD) is a clinicopathologic spectrum of liver pathologies associated with excessive accumulation of fat in the liver. This spectrum is continuous but can be graded based on pathological features; in increasing severity, these are: bland steatosis,

• br Materials and met http

  2023-10-09

  

  Materials and methods Results The values for body weight are shown in Fig. 1. Body weight was measured every day. The body weight of the young mice in the control (i.e. no-stress) group was not significantly different from that of the young mice in the stress group. However, the middle-aged mi

• br Results br Discussion Many tumor cells rely

  2023-10-09

  

  Results Discussion Many tumor Nitrotetrazolium Blue chloride rely on EAAs to provide fundamental building blocks for macromolecular biosynthesis because they cannot synthesize EAAs de novo (Hattori et al., 2017; Sheen et al., 2011). Therefore, they must use highly effective transporters to max

• br Materials and Methods br Results In

  2023-10-09

  

  Materials and Methods Results In the Base Analysis (53% of patients having access to the ALK test in both Current and Alternative Scenarios), a total of 16,583 patients were tested of whom 1,252 were assumed to be ALK-positive. A more extensive use of Ventana in the Alternative Scenario determ

• HT modulates cortical and hippocampal pyramidal cell functio

  2023-10-08

  

  5-HT modulates cortical and hippocampal pyramidal cell function in a very complex manner, since most 5-HT receptor subtypes (excitatory as well as inhibitory) are expressed on pyramidal 2143 as well as GABAergic interneurons that exert inhibitory control over pyramidal cells (Leiser et al., 2015, Da

• br Conflict of interest statement br Benign prostatic hyperp

  2023-10-08

  

  Conflict of interest statement Benign prostatic hyperplasia (BPH) is a highly complex process characterized by an increased number of epithelial and stromal ski or skii australia in the transition zone. , , Autopsy studies by McNeal detail the evolution of histological changes within these 2 ce

• During the year study period of men

  2023-10-08

  

  During the 4-year study period, 19.9% of men in the dutasteride group developed prostate cancer as compared to 25.1% in the placebo group, which represents an absolute risk ae3 australia of 5.1% for men taking dutasteride (Pe weighed against the prospect of undesirable sexual side effects and decre

• In order to increase the oral bioavailability abiraterone is

  2023-10-08

  

  In order to increase the oral bioavailability, abiraterone (157) is being used in the form of its 3β-acetoxy prodrug, abiraterone acetate (156). In spite of the fact that high-fat meals increase the oral pemetrexed disodium of abiraterone acetate (156), it is recommended that this drug should be ta

• br Perspective AA LA and other PUFAs and their lipid

  2023-10-08

  

  Perspective AA, LA and other PUFAs and their lipid metabolites play an important role in human diseases. 12/15-LOX which is the metabolic enzyme of them plays an important role in the pathogenesis-related diseases such as atherosclerosis, diabetic nephropathy, neurological diseases and other path

• br Material and methods br Results

  2023-10-08

  

  Material and methods Results Discussion T2D is a substantial threat to global human health [31]. Obesity-associated chronic low-grade inflammation promotes insulin resistance and T2D [32]. In obese individuals, the production of numerous inflammatory molecules including IL-6 and TNF-a is up

• br Introduction Hepatocellular carcinoma HCC is

  2023-10-08

  

  Introduction Hepatocellular carcinoma (HCC) is an aggressive and malignant cancer detected in clinical practice, as it is the third key reason of tumor-related deaths worldwide, with > 800, 000 mortalities every year (Torre et al., 2015). Current treatments for HCC are surgical therapy, liver tr

• br Materials and methods br Results br Discussion Japanese

  2023-10-08

  

  Materials and methods Results Discussion Japanese encephalitis caused by JEV is characterized by rgd peptide neuron death. However, the underlying mechanism is not fully understood. We and other researchers have demonstrated that JEV induces apoptosis by ER stress-mediated IRE1/JNK and ROS-

• Our previous studies and others have

  2023-10-08

  

  Our previous studies and others have identified that the inhalational anesthetic isoflurane induces neuronal apoptosis via [Ca2+]i overload through the opening of synaptic voltage-dependent calcium channels (VDCCs) and the excessive Ca2+ release from the endoplasmic reticulum (Zhao et al., 2011; Zha

• Furthermore because most of foods and beverages have

  2023-10-08

  

  Furthermore, because most of foods and beverages have been consumed after processing, researchers have focused on the effects of processing (e.g. blanching, cooking, drying, cooling, freezing, high-pressure treatment, pulsed electric field) on total antioxidant capacity of foods. In general, there w

• Recently dairy proteins obtained from

  2023-10-08

  

  Recently, dairy proteins obtained from whey have received considerable attention for their antioxidant bioactivity (Bayram et al., 2008; Haraguchi et al., 2011; Zhang et al., 2012). Bovine whey proteins (WP) are widely used in various foods for their nutritional, health-promoting, and functional val

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