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br Author Contributions br Acknowledgments br Introduction
2021-06-09

Author Contributions Acknowledgments Introduction Osteoporosis is a common bone disease that frequently leads to disruption of the alveolar and systemic bones with age. Novel osteoanabolic strategies to treat osteoporotic bone loss or augment fracture repair efficiently are desired. Since b
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br Restenosis after angioplasty remains a
2021-06-09

Restenosis after angioplasty remains a remarkable challenge, although drug-eluting stents have reduced the incidence of restenosis considerably . Vascular smooth muscle Cy7.5 NHS ester (non-sulfonated) (VSMCs) play a pivotal role in the development of intimal thickening and restenosis. VSMCs prol
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The totality of evidence from randomized clinical trials sup
2021-06-09

The totality of evidence from randomized clinical trials supports the premise that worsening PKM2 inhibitor failure is a class effect of DPP-4 inhibitors. A meta-analysis by Verma et al. (54) of 100 randomized controlled clinical trials reported that the use of DPP-4 inhibitors was accompanied a si
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br DDR receptor and MMP expression Type II
2021-06-09

DDR2 receptor and MMP-13 expression Type II collagen protein in articular cartilage is highly stable structure as its half-life is 117 years [43]. The chondrocytes have limited ability to synthesis type II collagen protein in the matrix of mature articular cartilage once the collagen gets disrupt
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br Materials and methods br Acknowledgments br Introduction
2021-06-09

Materials and methods Acknowledgments Introduction Proton pumps convert the energy of high-energy compounds into the somatostatin agonist of protons across biomembranes. They play two physiological roles: pH regulation and the formation of proton-motive forces in their membranes. The simple
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ixazomib br Role of cysLT signaling
2021-06-09

Role of cysLT signaling on various neurological complications which are associated with Alzheimer’s disease Alzheimer’s disease, first described in 1906 by Alois Alzheimer, is a neurodegenerative disease and a very common cause of dementia progressively leading to death. Even though years of rese
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br Amygdala microcircuitry and fear learning Recent
2021-06-09

Amygdala microcircuitry and fear learning Recent work has begun to dissect functional amygdala circuits that are responsible for the acquisition and expression of fear learning. Ciocchi et al. (2010) identified separable populations of Otilonium Bromide within the CeAL that have opposite response
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The crystal structure of LiCoO is
2021-06-09

The crystal structure of LiCoO2 is presented in Fig. 1. We can notice that the Li and Co atoms occupy the centers of two different edge-sharing [CoO6]-octahedra, which results in formation of separate Li and Co layers. Hence, the layered structure of LiMO2 is able to intercalate lithium into transit
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Citrus comprising some of the most widely cultivated fruit
2021-06-09

Citrus [29], comprising some of the most widely cultivated fruit crops worldwide, has been consumed as a food and dietary supplement. According to traditional Chinese medicine, dry pericarp of Citrus, as a Chinese herbal remedy, is capable of regulating Qi and expelling phlegm, and has been used to
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It is generally thought that the nature of a
2021-06-09

It is generally thought that the nature of a memorial and the meaning attributed to it KY 02111 receptor by a tourist determines, at least in part, the behaviour that is socially appropriate (Mayo, 1988). Duncan (1995) argues however, that certain places are structured in such a way that they facil
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The need for dedicated DAPT updates
2021-06-09

The need for dedicated DAPT updates is well justified by the large amount of data and new information generated in the field over the past few years. As expected, the ACC/AHA and ESC updates contain large areas of overlap as well as some differences. Differences were largely explained by the differe
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br STAR Methods br Acknowledgments We thank members of R
2021-06-09

STAR★Methods Acknowledgments We thank members of R.L. lab and F. Schweisguth for critical reading of the manuscript. We are also grateful to F. Janody, M. Miura, C. Bökel, H.D. Ryoo, G. Jiménez, the Bloomington Drosophila Stock Center, the Drosophila Genetic Resource Center, the Vienna Drosoph
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Little information is available regarding the
2021-06-09

Little information is available regarding the expression of the different EP receptor subtypes on human monocytic cells, particularly those that are involved in downregulating cytokine production. The receptors are controlled by the respective genes for each receptor i.e. PTGER1–PTGER4 for EP1–EP4 r
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With respect to bone metabolism
2021-06-09

With respect to ‘bone metabolism and ossification’-related genes, treatment of SaOS-2 osteoblast-like G-36 with MS-10 up-regulated IGFBP-4, TG2, and SOST. Up-regulation of IGFBP-4 in SaOS-2 cells inhibits DNA and protein synthesis induced by IGF-1 (Kudo et al., 1995, Kudo et al., 1996). In addition,
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br Conflicts of interest br Acknowledgements br Introduction
2021-06-08

Conflicts of interest Acknowledgements Introduction Atherosclerosis is the number one cause of death in the United States and among the leading causes of morbidity and mortality globally [1]. Inflammation is critical in all stages of atherosclerosis from the formation of a plaque in the ves
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